Progesterone Receptors

Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity.

QCC-374 is prostanoid agonist potentially for the treatment of pulmonary arterial hypertension.