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Catalog No.
Product Name
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Product Citation
Sirtuin-1 (SIRT1) activator
SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.
AK-7 is a cell- and brain-permeable inhibitor of SIRT2 (IC50 = 15.5 μM).
AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM.
OSS-128167, also known as SIRT6-IN-1, is a potent and selective SIRT 6 inhibitor with IC50 value of 89 μM.
Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM.
UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM.
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