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Protein Tyrosine Phosphatase

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  1. A22295
    SC-43

    SHP-1 (PTPN6) agonist

    SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects.
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