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Product Citation
- Ethyl dirazepate is a drug which is a benzodiazepine derivative. It has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties.
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P2X7 receptor antagonist
JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively. -
partial M1 agonist and M2/M3 antagonist
Alvameline (Lu25-109) is a partial M1 agonist and M2/M3 antagonist. -
NMDA receptor partial agonist
Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist. -
BACE1 inhibitor
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. -
GABA receptor antagonist
Gabazine free base is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites.
