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Phosphorylases

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CP-91149

Catalog No. A11173
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HLGP Inhibitor

CP-91149 is a selective glycogen phosphorylase inhibitor.
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Tipiracil

Catalog No. A13098
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Thymidine phosphorylase inhibitor

Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Learn More

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FK866

Catalog No. A11279
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NMPRTase Inhibitor

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Learn More

Product Citations (4)

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- Takeshi Nakamura, .et al. Effects of NAD+ Synthesis Levels on Sirtuin 1 Deacetylase Activity in Mammalian Cells, Shimane Journal of Medical Science, 2022, 38 (2), 59-66
- Takeshi Katayoshi, .et al. Restoring NAD + by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes, J Photochem Photobiol B, 2021, Jun 12;221:112238 PMID: 34130091
- Yool Lee, .et al. Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle, Sci Adv, 2021, 7
- Peter M LoCoco, .et al. Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy, eLife, 2017, 6: e29626 PMID: 29125463
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K252a

Catalog No. A13897
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CaMK/Phosphorylase inhibitor

K252a is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively). Learn More

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Doxifluridine

Catalog No. A11847
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Thymidine phosphorylase activator

Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. Learn More

Product Citations (3)

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- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347