Proteases

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  1. Undecylenic acid is a fatty acid with a terminal double bond. Undecylenic acid is an active ingredient in medications for skin infections, and to relieve itching, burning, and irritation associated with skin problems.
  2. Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
  3. Tricaprilin, also known as Glyceryl trioctanoate, is a triglyceride drug candidate.
  4. Sodium deoxycholate is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
  5. Dichlorisone acetate is a Glucocorticoid.
  6. Bcl-2 Family activator

    (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  7. (R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA).
  8. β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury.
  9. 16-Dehydroprogesterone is a steroidal progestin.
  10. Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses.
  11. Aminoadipic acid is an intermediate in the metabolism of lysine and saccharopine.
  12. NADP is nicotinamide adenine dinucleotide phosphate, acting as a key cofactor for electron transfer in the metabolism of all organisms, being alternately oxidized (NADP+) and reduced (NADPH).
  13. 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia.
  14. cNIIIB nucleotidase inhibitor

    7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8????7.5??M.
  15. 1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.
  16. (S)-3,4-Dihydroxybutyric acid is a normal human urinary metabolite that is excreted in increased concentration in patients with succinic semialdehyde dehydrogenase (SSADH) deficiency.
  17. Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
  18. 4-Guanidinobutanoic acid is a normal metabolite present in low concentrations.
  19. Ureidopropionic acid is an intermediate in the metabolism of uracil.
  20. 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.
  21. Leucyl-phenylalanine belongs to the class of organic compounds known as dipeptides.
  22. 3-Methyladipic acid is the final metabolite in the ω-oxidation pathway.
  23. Pi-Methylimidazoleacetic acid is a potential neurotoxin.
  24. Biotin sulfone is first isolated as a natural metabolite of biotin.
  25. Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines.
  26. 8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.
  27. 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81.
  28. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions.
  29. trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human.
  30. p-Synephrine is an organic compound, found in multiple biofluids, such as urine and blood.
  31. Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.
  32. Orotidine is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA, and plays a crucial role in contemporary biology.
  33. Stearoylcarnitine is a fatty ester lipid molecule.
  34. Tetradecanoylcarnitine is a human carnitine involved in β-oxidation of long-chain fatty acids.
  35. Butyrylcarnitine is a metabolite in plasma, acts as a biomarker to improve the diagnosis and prognosis of heart failure, and is indicative of anomalous lipid and energy metabolism.
  36. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.
  37. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases. Isobutyryl-L-carnitine is a member of the class of compounds known as acyl carnitines.
  38. Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.
  39. L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine.
  40. Docosapentaenoic acid (22n-3) is a component of phospholipids found in all animal cell membranes.
  41. L-Palmitoylcarnitine is a fatty acid metabolite.
  42. L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease.
  43. Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars.
  44. 1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
  45. 3-Methyluridine is a modified nucleoside of cellular RNA.
  46. N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.
  47. 1-Methylguanosine is a methylated nucleoside.
  48. 5-Methylcytidine is a pyrimidine nucleoside detected in multiple biofluids.
  49. Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. It is a biochemical compound involved in many metabolic pathways, including the Calvin cycle in plants and glycolysis.
  50. Eicosadienoic acid is a rare, naturally occurring n-6 polyunsaturated fatty acid found mainly in animal tissues.

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