D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator.
Ceramide is a ceramide shown to be a potent modulator of proliferation and differentiation, used as a tool for studying the complex signaling associated with the ceramides.