Tie-2

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  1. Tie-2 inhibitor

    AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM).
  2. Tie2 and TrkA/B inhibitor

    CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.

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