Acyltransferases

ATR-101 is in clinical development for the treatment of adrenocortical carcinoma (ACC).

Nevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM.