Membrane Transporters-Ion Channels

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  1. SGLT2 inhibitor

    Tofogliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
  2. TRPM8 agonist

    D-3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity.
  3. H+/K+-ATPase inhibitor

    Picoprazole is a specific inhibitor of H+/K+-ATPase with IC50 of 3.1??0.4 μM.
  4. inhibitor of Kv2.1 and Kv2.2

    RY785 (Kv2-IN-A1) is an inhibitor of Kv2.1 and Kv2.2.

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