Membrane Transporters-Ion Channels

Tofogliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.

Picoprazole is a specific inhibitor of H+/K+-ATPase with IC50 of 3.1??0.4 μM.

RY785 (Kv2-IN-A1) is an inhibitor of Kv2.1 and Kv2.2.