Proton Pump

Tenatoprazole is a prodrug of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 uM.

Rabeprazole is an inhibitor of H(+)-K(+)-exchanging atpase in gastric parietal cells.

Soraprazan is a reversible, and fast-acting inhibitor of gastric H+/K+ ATPase.

KM 91104 is a cell-permeable inhibitor of V-ATPase that specifically targets the interaction between V-ATPase subunit a3 and subunit B2.