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Ubiquitin
E3 ligase

E3 ligase

Catalog No.

Product Name

Application

Product Information

Product Citation

A13654

HLI-98C

Hdm2 ubiquitin ligase Inhibitor

HLI-98C, an analog, indeed inhibited Mdm2 E3 ligase activity.

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A21483

WS-383

DCN1-UBC12 interaction inhibitor

WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2.

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