Apoptosis Inducers



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Catalog No. Product Name Application Product Information
A11635

Cyclophosphamide monohydrate

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Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations.
A11279

FK866

NMPRTase Inhibitor
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
A11988

Gambogic acid

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Gambogic acid is a natural product isolated from the Garcinia hanburyi tree. Induces apoptosis in several tumor cell lines including T47D cells.
A13070

LY573636 (Tasisulam)

Apoptosis inducer
LY573636 is a potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. LY573636-induced apoptosis occurs by a mitochondrial-targeted mechanism.
A10582

Methylprednisolone

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Methylprednisolone is an apoptosis inducer and was also found to inhibit human small cell lung cancer cell growth in vitro.
A10955

TW-37

Bcl-2 inhibitor
TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer mediated through a novel pathway involving inactivation of Notch-1 and Jagged-1.

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