Synthases / Synthetases



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Catalog No. Product Name Application Product Information
A10776 SALE

Raltitrexed (Tomudex)

DNA/RNA Synthesis inhibitor
Raltitrexed (Tomudex) is an inhibitor of thymidylate synthase and also is one of the strongest antimetabolites in use.
A13483

YM-53601

Squalene synthase inhibitor
YM-53601 is a novel squalene synthase inhibitor. It suppresses lipogenic biosynthesis and lipid secretion in rodents.
A15331

C 75

FASN Inhibitor
C 75 is an inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice.
A15466 SALE

Eliglustat tartrate

Glucocerebroside synthase inhibitor
Commonly used as the tartrate salt, Eliglustat is believed to work by inhibition of glucosylceramide synthase.
A11488

MF63

MPGES-1 inhibitor
MF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively.
A15442 SALE

Genz-123346 free base

GL1 synthase Inhibitor
Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM.
A16202

Buthionine Sulphoximine

γ-glutamylcysteine synthetase inhibitor
Buthionine Sulphoximine is a gamma-glutamylcysteine synthetase inhibitor potentially for the treatment of solid tumors.
A16329

AN3365

leucyl-tRNA synthetase inhibitor
AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor.
A14937

Bismuth Subcitrate Potassium

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Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.
A13999

Triacsin C

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Triacsin C, originally isolated from Streptomyces sp., is an inhibitor of long fatty acid acyl-CoA synthetase (IC50 = 6.3 uM in Raji cells).
A13436 SALE

Anidulafungin

glucan synthase inhibitor
Anidulafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1995 and commercially developed by Eli Lilly. Anidulafungin inhibits the synthesis of ??-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi and is extensively referenced in the literature with over 400 citations.
A11113 SALE

Pneumocandin B0

β-1,3-Glucan Synthase Inhibitor
Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
A10050

Alendronate sodium hydrate

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Alendronate is a nitrogen-containing bisphosphonate that is commonly used in the treatment of osteoporosis and other metabolic bone diseases.
A12992

HQL-79

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HQL-79 is a selective inhibitor of hematopoietic prostaglandin D (PGD) synthase, that structurally is a synthetic tetrazole compound originally prepared as a possible antihistamine.
A13269

Caspofungin

1,3-β-D-glucan synthase inhibitor
Caspofungin is an antifungal medicine. It is used to help the body overcome serious fungus infections, including Candida and Aspergillosis infections. It is also used to treat serious fungus infections when other medicines (e.g., amphotericin B, itraconazole) have failed.
A13270 SALE

Micafungin

1,3-β-D-glucan synthase inhibitor
A12258 SALE

HPGDS inhibitor 1

HPGDS inhibitor
HPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM.
A13261

Nolatrexed Dihydrochloride

Thymidylate synthase inhibitor
Nolatrexed Dihydrochloride is an antifolate thymidylate synthase inhibitor.
A14107

C75

FASN inhibitor
C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer.
A14938

Bismuth Subsalicylate

-
Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.

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