Dopamine Receptors

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  1. D2 receptor antagonist

    Adoprazine is part of the Antidepressant Agent group
  2. dopamine D3 receptor antagonist

    SB-277011 is a drug which acts as a potent and selective dopamine D3 receptor antagonist which is around 80-100x selective for D3 over D2 and lacks any partial agonist activity.
  3. Dopamine receptor antagonist

    cis-(Z)-Flupentixol dihydrochloride is a dopamine receptor antagonist, antipsychotic, neuroleptic agent.
  4. D2 receptor antagonist

    Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7).
  5. D1/D5 receptor antagonist

    SCH 23390 hydrochloride is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively).
  6. D3/D2 Dopamine Receptor Antagonist

    Cariprazine hydrochloride is a novel antipsychotic drug candidate that exhibits high selectivity and affinity to dopamine D3(Ki=0.09 nM) and D2 (Ki=0.5 nM) receptors and moderate affinity to serotonin 5-HT(1A) receptors.
  7. Dopamine D1/2 receptor antagonist

    Melitracen HCl ia potential dopamine D1/2 receptor antagonist used to treat depression. It is often co-administered with flupenthixol as a treatment for trigeminal neuralgia. It does not effect cardiovascular function.
  8. Dopamine D4 receptor antagonist

    A-381393 is a potent and selective agonist of the dopamine D4 receptor.
  9. dopamine autoreceptor antagonist

    CGP 25454A is a novel and selective presynaptic dopamine autoreceptor antagonist.
  10. dopamine D2 receptor antagonist

    Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor.
  11. dopamine D2 receptor antagonist

    JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.

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