GPCR/G Protein

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Catalog No.
Product Name
Application
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Product Citation
  1. mGluR2 PAM

    JNJ-40411813 is a novel mGluR2 PAM.
  2. mGluR-2 modulator

    JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 receptor.
  3. GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120).
  4. GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120).
  5. mGluR5 Modulator

    VU0364289 is a novel N-aryl piperazine mGlu5 positive allosteric modulator.
  6. SK2 modulator

    NS13001 is a selective SK2/3 modulator that acts as a potential therapeutic agent for treatment of SCA2 and possibly other cerebellar ataxias.
  7. 5-HT1 receptor modulator

    NEO 376 is a selective modulator of 5-HT1 receptor, GABA receptor and dopamine receptor, with anti-psychotic actively.
  8. mGluR1 receptors Modulator

    DFMTI is an allosteric negative modulator of mGluR1 receptors.
  9. human CX3CR1 receptor modulator

    AZD8797 is an allosteric non-competitive and orally active modulator of the human CX3CR1 receptor; antagonizes CX3CR1 and CXCR2 with Kis of 3.9 and 2800 nM, respectively.
  10. mGluR5 positive allosteric modulator

    (R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .
  11. MRGPRX1 positive allosteric modulator

    ML382 is a potent and selective MRGPRX1 (Mas-related G protein-coupled receptor X1, MrgX1) positive allosteric modulator, with an EC50 of 190 nM.

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