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$0.00 Aromatase
| Catalog No. | Inhibitor Name | Aromatase |
|---|---|---|
| A10523 | Letrozole | **** |
| A10075 | Anastrozole | *** |
| A10378 | Exemestane | *** |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Fulvestrant (Faslodex)
Catalog No. A10410 Aromatase inhibitorFulvestrant is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. Learn More -
Chrysin
Catalog No. A10209 Aromatase InhibitorChrysin is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea). It has been shown to induce an anti-inflammatory effect, most likely by inhibition of COX-2 expression and via IL-6 signaling. In rodent in vivo studies, chrysin was found anxiolytic. Learn More -
Alpha-Naphthoflavone
Catalog No. A18474 aromatase inhibitorAlpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. Learn More -
Fadrozole hydrochloride
Catalog No. A21258 Aromatase inhibitorFadrozole hydrochloride is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. Learn More -
Anastrozole
Catalog No. A10075 Aromatase inhibitorAnastrozole is a third-generation nonsteroidal selective aromatase inhibitor. It may offer greater selectivity compared with other aromatase inhibitors, being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids. Learn More -
Exemestane
Catalog No. A10378 Aromatase inhibitorExemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. Learn More -
Letrozole
Catalog No. A10523 Aromatase inhibitorLetrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1–3 μg/kg p.o.) Learn More -
Fadrozole
Catalog No. A11088 Aromatase inhibitorFadrozole is a nonsteroidal aromatase inhibitor exhibiting a very potent and selective inhibitory effect of the aromatase enzyme system in vivo and estrogen biosynthesis in vivo. Learn More
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