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Metabolism

Metabolism

Catalog No.

Product Name

Application

Product Information

Product Citation

A12154

RWJ-445167

dual inhibitor of thrombin and factor Xa

RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

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A22710

TM5007

PAI-1 inhibitor

TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 29 uM.

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