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Catalog No.
Product Name
Application
Product Information
Product Citation
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NAMPT inhibitor
CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM. -
NAMPT activator
P7C3-A20 is a potent neuroprotective agent.- Oku H, .et al. , Invest Ophthalmol Vis Sci, 2017, Sep 1;58(11):4877-4888 PMID: 28973334
- Oku H, .et al. , Jpn J Ophthalmol, 2017, Mar;61(2):195-203 PMID: 28032230
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NAMPT inhibitor
STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia. -
PAK4/NAMPT Inhibitor
KPT 9274 ( ATG-019) is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT. It shows an IC50 of ~120 nM for NAMPT in a cell-free enzymatic assay.