IRE1

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Catalog No.
Product Name
Application
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  1. IRE1α inhibitor

    APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
  2. mono-selective IRE1α inhibitor

    Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
  3. Hydroxy aryl aldehydes (HAA) inhibitor

    MKC9989 is a Hydroxy aryl aldehydes (HAA) inhibitor and also inhibits IRE1α with an IC50 of 0.23 to 44 μM.

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