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Protein serine-threonine phosphatase
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FK-506 is an immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system and so lower the risk of organ rejection. It reduces interleukin-2 (IL-2) production by T-cells.
2 publications
Ogawa Y, .et al. , Neurobiol Dis , 2018, Oct;118:142-154 PMID: 30026035 Yuko Okamoto, .et al. , J Drug Deliv Sci Technol , 2018, 47: 62-66
Ascomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.
Calcineurin-NFAT inhibitor
INCA-6 is a potent and selective inhibitor of calcineurin-NFAT (Nuclear Factor of Activated T cells) signaling.
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Inhibitor
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$0.00 - $100.00