Immunology & Inflammation related
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COX inhibitor
Flufenamic acid is a nonsteroidal anti-inflammatory drug (NSAID). Inhibits calcium-activated chloride channels (CaCCs). Also increases currents through TRPC6 channels and inhibits currents through TRPC3 and TRPC7 channels.
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CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
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21-Deacetoxy Deflazacort is an intermediate of Deflazacort, a systematic corticosteroid.
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Anti-Inflammatory Peptide 1, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I.
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LTA4 hydrolase Inhibitor
SC 57461A is a potent and competitive inhibitor of recombinant human leukotriene A4 hydrolase in vitro (Askonas et al., 2002).
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Immunomodulator
Aceneuramic acid is an immunomodulator potentially for treatment of hereditary inclusion body myopathy (HIBM).
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Eugenol is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.
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Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).
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Loxoprofen is a non-steroidal anti-inflammatory drug.
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- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
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Prostaglandin F2α is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
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- Michel R Corboz, .et al. Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human lung fibroblasts, Prostaglandins Other Lipid Mediat, 2020, Oct 1;152:106486 PMID: 33011365
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Benzydamine Hcl is a locally-acting nonsteroidal anti-inflammatory drug with local anaesthetic and analgesic properties; selectively binds to prostaglandin synthetase and has notable in vitro antibacterial activity.
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