Raf

Raf265 derivative is a derivative of Raf265 that is an oral, highly selective RAF and VEGFR kinase inhibitor with IC50 of of 5 to 10 μM.

Balamapimod, also known as MKI-822, is a Ras/Raf/MEK inhibitor.

LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 .

B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM.