Neuronal Signaling

5-hydroxymethyl tolterodine is a metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.

Revefenacin is potent and selective muscarinic receptor antagonist in development for the treatment of COPD.

Cimetropium Bromide (DA-3177) is a mAChR antagonist for long-term treatment of irritable bowel syndrome.

Elucaine is a muscarinic acetylcholine receptor antagonist with anti-ulcerative activity.

YM-58790 is a potent antagonist of M3 muscarinic receptor, with Ki of 15 nM.