Proteases

HU-083 is a HU-083 is a Glutamine antagonist, a DON prodrug., a DON prodrug.

Voclosporin is a calcineurin (CN) inhibitor.

MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of appr 1 μM, 200-fold preference over TCPTP (IC50, 224 μM).

MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).

SU 4942 is a tyrosine kinase signal transduction modulator, targeting VEGF and ECGF.