Purinergic (P2Y) Receptors

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  1. Elinogrel

    Catalog No. A21468
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    platelet P2Y12 antagonist
    Elinogrel (PRT060128) is a potent, direct acting, competitive, and reversible platelet P2Y12 antagonist (IC50=20 nM). It is orally and intravenously available and has potent antiplatelet effects. Learn More
  2. Clopidogrel thiolactone

    Catalog No. A20862
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    P2Y12 receptor inhibitor
    Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent. Learn More
  3. Vicagrel

    Catalog No. A18586
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    P2Y12 platelet inhibitor
    Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis. Learn More
  4. Cangrelor Tetrasodium

    Catalog No. A17919
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    P2Y12 receptors inhibitor
    Cangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion. Learn More
  5. BPTU

    Catalog No. A16952
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    P2Y1 antagonist
    BPTU is a P2Y1 antagonist. It has been shown to provide antithrombotic efficacy and reduce bleeding liability. Learn More
  6. Prasugrel (Effient)

    Catalog No. A10748
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    platelet inhibitor
    Prasugrel is a novel platelet inhibitor used for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome who are to be managed with PCI. Learn More
  7. Prasugrel Hydrochloride

    Catalog No. A16144
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    P2Y12 antagonist
    Prasugrel is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events. Learn More
  8. Methylthioadenosine

    Catalog No. A16106
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    Methylthioadenosine is a naturally occurring sulfur-containing nucleoside present in all mammalian tissues. Learn More
  9. AZD1283

    Catalog No. A15443
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    P2Y12 receptor antagonist
    AZD1283 is a potent antagonist of the P2Y12 receptor with EC50 of 3.0 ug/kg/min, TI >10; with binding IC50 of 11 nM. Learn More
  10. MRS 2578

    Catalog No. A11486
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    P2Y6 Receptor Antagonist
    MRS 2578 is a selective antagonist of P2Y6 nucleotide receptors Learn More
  11. Ticagrelor (AZD6140)

    Catalog No. A11238
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    P2Y12 antagonist
    Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation. Learn More
  12. (+)-Clopidogrel hydrogen sulfate (Plavix)

    Catalog No. A10233
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    (+)-Clopidogrel hydrogen sulfate is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Learn More
  13. Clopidogrel

    Catalog No. A21206
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    P2Y12 receptor inhibitor
    Clopidogrel is a well-known and orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Learn More

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