VDA

Inhibitory Selectivity
Catalog No.Inhibitor Name VDAOther
A10324DMXAA (ASA404, Vadimezan)
**
A10654NPI-2358 (Plinabulin)
***
A12658Verteporfin
YAP/TEAD interaction

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

4 Item(s)

per page

Set Descending Direction
  1. NPI-2358 (Plinabulin)

    Catalog No. A10654
    Quick View
    Microtubule Inhibitor
    NPI-2358 is a synthetic analog of NPI-2350, a natural product isolated from Aspergillus sp., which depolymerizes microtubules in A549 human lung carcinoma cells. Learn More
  2. DMXAA (ASA404, Vadimezan)

    Catalog No. A10324
    Quick View
    Vascular Disrupting Agent (VDA)
    DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression. Learn More
  3. Verteporfin

    Catalog No. A12658
    Quick View
    YAP inhibitor
    Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin. Learn More
  4. Oxi 4503

    Catalog No. A14352
    Quick View
    VDA
    Oxi4503 is a novel vascular targeting agent that effects on blood flow and antitumor activity in comparison to combretastatin A-4 phosphate. Learn More

4 Item(s)

per page

Set Descending Direction
Rewards