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GPCR/G Protein
Metabotropic glutamate receptors (mGluR)

Metabotropic glutamate receptors (mGluR)

Catalog No.

Product Name

Application

Product Information

Product Citation

A11126

BINA

mGluR2 modulator

BINA is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2).

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A12139

VU 0364770

mGlu4 receptors modulator

VU 0364770 is a positive allosteric modulator at mGlu4 receptors with EC50 value of 290 nM in mGlu4-expressing HEK 293 cells.

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A14330

JNJ 42153605

mGluR-2 modulator

JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 receptor.

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A15811

CBiPES HCl

mGlu2 receptor modulator

CBiPES hydrochloride is a selective positive allosteric modulator of the mGluR-2 with IC50 value of 98.2 nM

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A15832

VU0364289

mGluR5 Modulator

VU0364289 is a novel N-aryl piperazine mGlu5 positive allosteric modulator.

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A20558

DFMTI

mGluR1 receptors Modulator

DFMTI is an allosteric negative modulator of mGluR1 receptors.

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A20732

JNJ-46778212

mGlu5 modulator

JNJ-46778212 (VU 0409551) is an mGlu5 positive allosteric modulator with an EC50 of 260 nM.

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A20922

ADX88178

mGluR4 PAM

ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4.

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A21887

(R)-ADX-47273

mGluR5 positive allosteric modulator

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .

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