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Catalog No.
Product Name
Application
Product Information
Product Citation
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Smoothened Inhibitor
LDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. -
Smoothened Inhibitor
PF-5274857 is a novel Smo antagonist that specifically binds to Smo with a K(i) of 4.6 ?? 1.1 nmol/L and completely blocks the transcriptional activity of the downstream gene Gli1 with an IC(50) of 2.7 ?? 1.4 nmol/L in cells. -
Smoothened inhibitor
BMS-833923 (or XL-139) is an orally bioavailable small-molecule SMO (Smoothened) inhibitor with potential antineoplastic activity.- Valérian Pasche, .et al. , Parasit Vectors, 2018, 11: 298 PMID: 29764454
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Smoothened inhibitor
PF-04449913 is a potent and orally bioavailable inhibitor of smoothened.