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Product Citation
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LY2886721 is a novel potent agent that is used to treat Alzheimer's Disease in preclinical experiments.
- Naomi Ito, .et al. , Br J Pharmacol, 2017, Mar; 174(5): 386-395 PMID: 28012171
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LY2811376 is the first orally available non-peptidic BACE1 inhibitor that produces profound Aβ-lowering effects in animals.
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β-secretase/BACE1 inhibitor
Verubecesta is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.
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LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM.
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Inhibitor
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Beta-secretase (BACE)
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