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| Catalog No. | Inhibitor Name | CETP |
|---|---|---|
| A11084 | Anacetrapib (MK-0859) | *** |
| A11242 | Torcetrapib (CP-529414) | ** |
| A11213 | JTT-705 (Dalcetrapib) | * |
| A11397 | Evacetrapib (LY2484595) | **** |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
6 Item(s)
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CKD-519
Catalog No. A18873 CETP inhibitorCKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor being developed for the treatment of dyslipidemia to raise high-density lipoprotein cholesterol. Single doses of CKD-519 up to 400 mg were well tolerated and showed potent inhibition of CETP activity. Learn More -
CETP-IN-3
Catalog No. A18878 CETP inhibitorCETP-IN-3 (Compound 13) is an small molecule inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP. Learn More -
Anacetrapib (MK-0859)
Catalog No. A11084 CETP inhibitorAnacetrapib (MK-0859) is a CETP inhibitor being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Learn More -
JTT-705 (Dalcetrapib)
Catalog No. A11213 CETP inhibitorJTT-705 (Dalcetrapib) is a CETP inhibitor.Inhibition of CETP is a target to increase HDL-cholesterol and potentially reduce atherosclerosis. Learn More -
Torcetrapib (CP-529414)
Catalog No. A11242 CETP inhibitorTorcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM. Learn More -
Evacetrapib (LY2484595)
Catalog No. A11397 CETP inhibitorEvacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3. Learn More
6 Item(s)
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