Chloride Channels
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VX-770 (Ivacaftor)
Catalog No. A10985 CFTR activatorVX-770 (Ivacaftor) is known as a CFTR potentiator. Learn More -
Ivermectin
Catalog No. A10490 Ivermectin is a broad-spectrum antiparasitic avermectin medicine. Learn More -
Talniflumate
Catalog No. A13339 CaCC blockerTalniflumate is a calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker; reduces mucin synthesis and release in cell culture and animal models. Learn More -
CaCCinh-A01
Catalog No. A15469 CaCCs InhibitorCaCCinh-A01 inhibits CaCC currents in human bronchial and intestinal cells. Also inhibits TMEM16A channels (IC50 = 2.1 uM, in TMEM16A-expressing FRT cells). Learn More -
T16Ainh-A01
Catalog No. A15470 TMEM16A InhibitorT16Ainh-A01 is a selective TMEM16A calcium-activated chloride channel inhibitor that strongly inhibits chloride current in salivary gland cells. Learn More -
Eact
Catalog No. A16179 CaCC activatorEact activates the Calcium-activated Chloride channel (CaCC) TMEM16A CaCC. Learn More -
NPPB
Catalog No. A16981 chloride channel blockerNPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. Learn More