Chloride Channels

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  1. VX-770 (Ivacaftor)

    Catalog No. A10985
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    CFTR activator
    VX-770 (Ivacaftor) is known as a CFTR potentiator. Learn More
  2. Ivermectin

    Catalog No. A10490
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    Ivermectin is a broad-spectrum antiparasitic avermectin medicine. Learn More
  3. Talniflumate

    Catalog No. A13339
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    CaCC blocker
    Talniflumate is a calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker; reduces mucin synthesis and release in cell culture and animal models. Learn More
  4. CaCCinh-A01

    Catalog No. A15469
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    CaCCs Inhibitor
    CaCCinh-A01 inhibits CaCC currents in human bronchial and intestinal cells. Also inhibits TMEM16A channels (IC50 = 2.1 uM, in TMEM16A-expressing FRT cells). Learn More
  5. T16Ainh-A01

    Catalog No. A15470
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    TMEM16A Inhibitor
    T16Ainh-A01 is a selective TMEM16A calcium-activated chloride channel inhibitor that strongly inhibits chloride current in salivary gland cells. Learn More
  6. Eact

    Catalog No. A16179
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    CaCC activator
    Eact activates the Calcium-activated Chloride channel (CaCC) TMEM16A CaCC. Learn More
  7. NPPB

    Catalog No. A16981
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    chloride channel blocker
    NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. Learn More

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