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Catalog No.
Product Name
Application
Product Information
Product Citation
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TLR7 agonist
Imiquimod (Aldara) is a a heterocyclic imidazoquinoline amide that acts as an immune response modifier.- David Diaz-Carballo, .et al. , Commun Biol, 2021, Mar 3;4(1):276 PMID: 33658617
- Kunishita Y, .et al. , Front Immunol, 2020, Feb 7;11:98 PMID: 32117252
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TLR7 agonist
PF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociate its antiviral and inflammatory activities. -
TLR8 agonist
VTX-2337 is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential immunostimulating and antineoplastic activities.- Yinwen Cheng, .et al. , Sci Rep, 2021, Jan 15;11(1):1535 PMID: 33452311
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TLR7 agonist
GS-9620 is a potent and selective orally active small molecule agonist of Toll-like receptor 7.- Yu-Geun Ji, .et al. , J Pharm Biomed Anal, 2019, 12 November, 112987
- Zhikuan Zhang, .et al. , Cell Reports, 2018, 25(12): 3371-3381.e5 PMID: 30566863
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TLR7 agonist
Isatoribine is a novel guanosine analogue showing immunostimulatory activity both in vivo and in vitro. -
TLR7/8 Agonist
Resiquimod is an immune response modifier that acts as a potent TLR 7/8 agonist. Phase 2. -
TLR7 agonist
TLR7-agonist-1 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM. -
TLR7 agonist
Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. CAS: 1159840-61-5 (TFA) 1020412-43-4 (free base) -
TLR7 agonist
TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM. -
TLR7/8 agonist
Telratolimod is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity. -
TLR7/8 agonist
TLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline.