LXR

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  1. AZ876

    Catalog No. A21026
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    LXR agonist
    AZ876 is a novel high-affinity LXR agonist. Learn More
  2. RGX-104 free Acid

    Catalog No. A21513
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    LXR agonist
    RGX-104 free Acid is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. Learn More
  3. LXR-623

    Catalog No. A21366
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    LXRα and full LXRβ agonist
    LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively. Learn More
  4. Rovazolac

    Catalog No. A18354
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    liver x receptor (LXR) modulator
    Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1. Learn More
  5. GSK-2033

    Catalog No. A17017
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    LXR antagonist
    GSK-2033 is a potent cell-active LXR antagonist (pIC50 = 7.5). It enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells and is cell permeable. Learn More
  6. SR9238

    Catalog No. A15763
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    LXR Inverse Agonist
    SR9238 is a potent and selective LXR inverse agonist (IC50 values are 43 and 214 nM for LXRβ and LXRα, respectively). Learn More
  7. SR9243

    Catalog No. A15535
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    LXR agonist
    SR9243 is a potent and selective LXR inverse agonist. SR9243 kills cancer cells by inhibiting lipid production and the Warburg effect. It induces cell death in multiple types of cancer and does not cause the side effects that have derailed previous attempts to target these processes. Learn More
  8. Sobetirome

    Catalog No. A15241
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    TRβ agonist
    Sobetirome is a thyroid hormone receptor β (TRβ)-specific agonist, Sobetirome is designed to bind selectively to TRβ-1 with EC50 of 0.16 μM. Learn More
  9. GW3965

    Catalog No. A15100
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  10. Mogroside II A2

    Catalog No. A12166
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    Mogroside II-A2, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities. Learn More
  11. Cerpegin

    Catalog No. A12865
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    Cerpegin is a naturally occurring pyridinone alkaloid isolated from Roxb, a tradional indian medicine used as an anti-inflammatory, analgesic, antiulcer and tranquilizer. Learn More
  12. T0901317

    Catalog No. A12652
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    LXR/FXR agonist
    T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively Learn More
  13. GW3965 HCl

    Catalog No. A11204
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    LXR-like receptors agonist
    GW3965 HCl is a selective and orally active liver X receptor (LXR) full agonist. Learn More

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