Others

Erythropterin is a Pterin derivative that belongs in a group of heterocyclic compounds that are frequently found in biological systems.

Collagen proline hydroxylase inhibitor-1 is an antifibroproliferative agents.

D-Fagomine is an iminosugar originally isolated from seeds of buckwheat (Fagopyrum sculentum Moench)

Glyoxalase I inhibitor is a potent Glyoxalase I inhibitor, candidate for anticancer agents.

Rocuronium (Org-9426) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.

RP 54275 (2-Octadecyl-1H-indole-5-carboxylic acid) is a novel hypocholesterolaemic drug.

Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.

WF-11899A is a novel antifungal lipopeptide antibiotics were isolated from the culture broth of Coleophoma empetri F-11899

N/A

20-HEDE (WIT 002) is an antagonist of 20-hydroxyeicosatetraenoic acid (20-HETE).

Ombrabulin is a synthetic water-soluble analogue of combretastatin A4, derived from the South African willow bush (Combretum caffrum), with potential vascular-disrupting and antineoplastic activities.

Teglarinad chloride, also known as GMX1777, is a water-soluble prodrug of a cyanoguanidine compound with potential antineoplastic activity. In vivo, teglarinad chloride is rapidly converted into active drug through hydrolytic cleavage of a carbonate ester bond.

RC-3095 is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.

Cardiolipin is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.

Ceftobiprole medocaril is a fifth-generation[2] cephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus, penicillin-resistant Streptococcus pneumoniae, Pseudomonas aeruginosa, and enterococci.

Cangrelor is a potent intravenous adenosine diphosphate-receptor antagonist

An Oxytetracycline metabolite

Lomifylline is a methylxanthine analogue which induces Ca2+-release from intracellular stores via the ryanodine receptor.

SNT207858 is a 22 nM MC4 antagonist with a 170-fold selectivity vs. MC3 and a 40-fold selectivity versus MC5.

4-Epi Minocycline is an impurity of Minocyclin, a second generation tetracycline antibiotic.

Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells.

GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4?CNKX2-5 transcriptional synergy with an IC50 of 3 μM.

NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 μM. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer.

Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators.

Laxogenin is a new steroidal sapogenin isolated from Smilax sieboldi Miq.

BMS-747158-02 is a fluorine 18?Clabeled pyridaben derivative designed as a new myocardial perfusion imaging agent for use with positron emission tomography (PET).

Metazathioprine is a methylated derivative of azathioprine (AZA). It demonstrated the greatest values of apparent and specific partition coefficients in n-octanol/phosphate buffer at pH 5.7 and pH 7.4 among purine derivatives such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and AZA.

CB-184 is a useful tools for characterization of sigma 2 receptors.

EC-17 is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity.

Anticancer agent 3 (Compound 4) is a anti-cancer agent.

Eteplirsen is an experimental drug, currently in clinical trials.

Beloranib, an analog of the natural chemical compound fumagillin, is an inhibitor of the enzyme METAP2.

SM-130686 is a potent, orally active growth hormone secretagogue, with around half the potency of the endogenous agonist ghrelin as a stimulator of growth hormone release.

WW298 is the first effective inhibitor of the Mdmx?€?p53 interaction.

YH249 is the first highly specific, direct p300/β-catenin antagonist.

PF6-AM is a new selective fluorescent indicator for hydrogen peroxide (H(2)O(2)), a tool to help discover new redox chemistry in biological systems.

sodium 4-pentynoate is a alkynylacetate analogue; can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types.

ST 2825 is a MyD88 pharmacologic inhibitor.

Finafloxacin hydrochloride is a fluoroquinolone compound.

EG01377 TFA salt is a selective neuropilin-1 (NRP1) antagonist. CAS: 2227996-00-9 (Free base)

Lofendazam is a benzodiazepine derivative that has sedative and anxiolytic effects.

EC1454 is an anti-tumor compound, extracted from US20170348376A1.

Thiamine diphosphate analog 1 is an analog of Thiamine diphosphate. Thiamine diphosphate is the active form of vitamin B1. Thiamine diphosphate a universal cofactor involved in pivotal cellular pathways.

Bz-Lys-Ome is a specific methyl ester substrate of trypsin.

MT-4 blocks the TG2/FN complex at the interface between cancer cells and the tumor niche. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.

PBDB-T is a wide bandgap polymer donor in Perylene diimide (PDI)-based polymer solar cells (PSCs).

ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes. ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 ??C.

NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity.

DS21360717 is a potent and orally active FER tyrosine kinase inhibitor, with an IC50 of 0.49 nM. Anti-cancer activity.

Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor extracted from patent WO2017201322A1, compound 13-R.