Proteases

1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.

(S)-3,4-Dihydroxybutyric acid is a normal human urinary metabolite that is excreted in increased concentration in patients with succinic semialdehyde dehydrogenase (SSADH) deficiency.

Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.

4-Guanidinobutanoic acid is a normal metabolite present in low concentrations.

Ureidopropionic acid is an intermediate in the metabolism of uracil.

7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

Leucyl-phenylalanine belongs to the class of organic compounds known as dipeptides.

3-Methyladipic acid is the final metabolite in the ω-oxidation pathway.

Biotin sulfone is first isolated as a natural metabolite of biotin.

8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.

2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81.

3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions.

trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human.

p-Synephrine is an organic compound, found in multiple biofluids, such as urine and blood.

Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.

Stearoylcarnitine is a fatty ester lipid molecule.

Butyrylcarnitine is a metabolite in plasma, acts as a biomarker to improve the diagnosis and prognosis of heart failure, and is indicative of anomalous lipid and energy metabolism.

Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases. Isobutyryl-L-carnitine is a member of the class of compounds known as acyl carnitines.

Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine.

L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease.

Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars.

1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.

3-Methyluridine is a modified nucleoside of cellular RNA.

N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.

1-Methylguanosine is a methylated nucleoside.

5-Methylcytidine is a pyrimidine nucleoside detected in multiple biofluids.

Eicosadienoic acid is a rare, naturally occurring n-6 polyunsaturated fatty acid found mainly in animal tissues.

Glycerol 3-phosphate is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.

LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site.

N-Acetylputrescine hydrochloride is a putrescine derivative.

Indolelactic acid is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures.

(S)-(?)-Perillyl alcohol is a monoterpene found in lavender, inhibits farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. Anti-cancer activity.

2-Oxovaleric acid is a keto acid that is found in human blood.

3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids.

1-Methyladenosine is an RNA modification originating essentially from two different reaction types, one catalyzed by enzymes and the other the result of the reaction of RNA with certain alkylating agents.

N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

Guanosine 5'-diphosphate is a nucleoside diphosphate. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.

5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

p-Hydroxymandelic acid is a valuable aromatic fine chemical and widely used for production of pharmaceuticals and food additives.

Delta-Tocopherol is an isomer of Vitamin E.

Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).

3-Hydroxyvaleric acid is a 5-carbon ketone body. 3-Hydroxyvaleric acid is anaplerotic, meaning it can refill the pool of TCA cycle intermediates.

3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.

10Z-Nonadecenoic acid is a kind of long-chain fatty acid with anti-tumor activity.

Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q.

1,2-Dipalmitoyl-sn-glycerol 3-phosphate is a phosphatidic acid.

8-Dehydrocholesterol elevated concentration is one of the diagnostic biochemical hallmarks of classical Smith-Lemli-Opitz syndrome (SLOS).

trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level.