NEDD8-activating Enzyme (NAE)

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  1. NAE inhibitor

    ZM223 is a non-sulfamide NEDD8 activating enzyme (NAE) inhibitor that inhibits HCT116 colon cancer cells with an IC50 value of 100 nM.
  2. NAE inhibitor

    TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.
  3. NAE inhibitor

    TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.

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