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$0.00 Protein serine/threonine phosphatase
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FK-506 (Tacrolimus)
Catalog No. A10389 mTOR inhibitorFK-506 is an immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system and so lower the risk of organ rejection. It reduces interleukin-2 (IL-2) production by T-cells. Learn More -
Ascomycin
Catalog No. A12592 calcineurin inhibitorAscomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases. Learn More -
Calcineurin Autoinhibitory Peptide
Catalog No. A15376 Calcineurin inhibitory peptide is a selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 uM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM). Learn More -
DL-AP3
Catalog No. A15378 mGluR1 antagonistDL-AP3, a racemic preparation of D-AP3 and L-AP3, is an inhibitor of phosphoserine phosphatase and an antagonist of the metabotropic glutamate receptor (mGluR), blocking phosphoinositide turnover mediated by the mGluR. Learn More -
INCA-6
Catalog No. A15380 Calcineurin-NFAT inhibitorINCA-6 is a potent and selective inhibitor of calcineurin-NFAT (Nuclear Factor of Activated T cells) signaling. Learn More -
Ascomycin (FK520)
Catalog No. A15788 Calcineurin/PP2B inhibitorAscomycin is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties. It has been researched for the treatment of autoimmune diseases and skin diseases, and to prevent rejection after an organ transplant. Learn More -
Cyclosporine
Catalog No. A15434 Calcineurin inhibitorCyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Learn More
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