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Catalog No.
Product Name
Application
Product Information
Product Citation
gamma-secretase modulator
E 2012 is γ-secretase inhibitor.
1 publications
Yesuvadian R, .et al. , Biochem Biophys Res Commun. , 2014, May 16;447(4):590-5 PMID: 24747079
gamma-secretase modulator
Flurizan is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits γ-secretase activity.
Gamma-secretase modulator
Compound W is a γ-secretase inhibitor that has been shown to lower the levels of secreted Aβ42 and Nβ25.
CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.
Wnt/beta-catenin modulator
KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells.
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