Thrombin
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Melagatran
Catalog No. A19083 Thrombin inhibitorMelagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Learn More -
RWJ-445167
Catalog No. A12154 dual inhibitor of thrombin and factor XaRWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. Learn More -
Inogatran
Catalog No. A13356 synthetic thrombin inhibitorInogatran (H-314-27) is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of arterial and venous thrombotic diseases. Learn More -
Odiparcil
Catalog No. A21584 indirect thrombin inhibitorOdiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) . Learn More -
Thrombin Inhibitor 2
Catalog No. A21814 thrombin inhibitorThrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity. Learn More -
BIBR-1048 (Dabigatran etexilate)
Catalog No. A10139 Thrombin inhibitorBIBR-1048 (Dabigatran etexilate) is an anticoagulant from the class of the direct thrombin inhibitors. Learn More -
BIBR 953 (Dabigatran, Pradaxa)
Catalog No. A10138 Thrombin inhibitorBIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. It has shown antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action and predictable pharmacodynamic response.
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Argatroban
Catalog No. A11774 Thrombin inhibitorArgatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. Learn More -
Bivalirudin
Catalog No. A15023 Reversible thrombin inhibitorBivalirudin is a synthetic 20 residue peptide which reversibly inhibits thrombin. Learn More -
Dabigatran etexilate mesylate
Catalog No. A15057 direct thrombin inhibitorDabigatran etexilate mesylate is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. Learn More -
Dabigatran ethyl ester
Catalog No. A15058 thrombin inhibitorDabigatran ethyl ester, which is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. Learn More -
Eltrombopag Olamine
Catalog No. A15078 c-mpl (TpoR) receptor agonistEltrombopag olamine is a new, orally active thrombopoietin-receptor (c-mpl) agonist that stimulates thrombopoiesis. Learn More -
Avatrombopag
Catalog No. A14087 Thrombopoietin(TPO) receptor agonistAvatrombopag is a novel orally-active thrombopoietin (TPO) receptor agonist. Learn More -
Ximelagatran
Catalog No. A12509 Thrombin inhibitorXimelagatran is an anticoagulant that has been investigated extensively as a replacement for warfarin that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy. Learn More -
PPACK
Catalog No. A16048 Thrombin inhibitorPPACK is a potent, selective and irreversible inhibitor of thrombin with a Ki value of 0.24 nM. Learn More -
TPO agonist 1
Catalog No. A16287 TPO agonistTPO agonist 1 can increase production of platelets by stimulating the TPO receptor in people with chronic ITP. Learn More