Thrombin

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  1. Thrombin Inhibitor 2

    Catalog No. A21814
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    thrombin inhibitor
    Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity. Learn More
  2. Odiparcil

    Catalog No. A21584
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    indirect thrombin inhibitor
    Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) . Learn More
  3. Inogatran

    Catalog No. A13356
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    synthetic thrombin inhibitor
    Inogatran (H-314-27) is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of arterial and venous thrombotic diseases. Learn More
  4. RWJ-445167

    Catalog No. A12154
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    dual inhibitor of thrombin and factor Xa
    RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. Learn More
  5. Melagatran

    Catalog No. A19083
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    Thrombin inhibitor
    Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Learn More
  6. TPO agonist 1

    Catalog No. A16287
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    TPO agonist
    TPO agonist 1 can increase production of platelets by stimulating the TPO receptor in people with chronic ITP. Learn More
  7. PPACK Dihydrochloride

    Catalog No. A16048
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    Thrombin inhibitor
    PPACK Dihydrochloride is a potent, selective and irreversible inhibitor of thrombin with a Ki value of 0.24 nM. Learn More
  8. Ximelagatran

    Catalog No. A12509
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    Thrombin inhibitor
    Ximelagatran is an anticoagulant that has been investigated extensively as a replacement for warfarin that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy. Learn More
  9. Avatrombopag

    Catalog No. A14087
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    Thrombopoietin(TPO) receptor agonist
    Avatrombopag is a novel orally-active thrombopoietin (TPO) receptor agonist. Learn More
  10. Eltrombopag Olamine

    Catalog No. A15078
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    c-mpl (TpoR) receptor agonist
    Eltrombopag olamine is a new, orally active thrombopoietin-receptor (c-mpl) agonist that stimulates thrombopoiesis. Learn More
  11. Dabigatran ethyl ester

    Catalog No. A15058
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    thrombin inhibitor
    Dabigatran ethyl ester, which is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. Learn More
  12. Dabigatran etexilate mesylate

    Catalog No. A15057
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    direct thrombin inhibitor
    Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. Learn More
  13. Bivalirudin Trifluoroacetate

    Catalog No. A15023
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    Reversible thrombin inhibitor
    Bivalirudin Trifluoroacetate is a synthetic 20 residue peptide which reversibly inhibits thrombin. Learn More
  14. Argatroban

    Catalog No. A11774
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    Thrombin inhibitor
    Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. Learn More
  15. BIBR 953 (Dabigatran, Pradaxa)

    Catalog No. A10138
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    Thrombin inhibitor

    BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. It has shown antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action and predictable pharmacodynamic response.

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  16. BIBR-1048 (Dabigatran etexilate)

    Catalog No. A10139
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    Thrombin inhibitor
    BIBR-1048 (Dabigatran etexilate) is an anticoagulant from the class of the direct thrombin inhibitors. Learn More

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