Thrombin

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Catalog No.
Product Name
Application
Product Information
Product Citation
  1. Thrombin inhibitor

    BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. It has shown antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action and predictable pharmacodynamic response.

  2. Thrombin inhibitor

    BIBR-1048 (Dabigatran etexilate) is an anticoagulant from the class of the direct thrombin inhibitors.
  3. Thrombin inhibitor

    Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor.
  4. dual inhibitor of thrombin and factor Xa

    RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.
  5. Thrombin inhibitor

    Ximelagatran is an anticoagulant that has been investigated extensively as a replacement for warfarin that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy.
  6. synthetic thrombin inhibitor

    Inogatran (H-314-27) is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of arterial and venous thrombotic diseases.
  7. Reversible thrombin inhibitor

    Bivalirudin is a synthetic 20 residue peptide which reversibly inhibits thrombin.
  8. direct thrombin inhibitor

    Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.
  9. thrombin inhibitor

    Dabigatran ethyl ester, which is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity.
  10. Thrombin inhibitor

    PPACK is a potent, selective and irreversible inhibitor of thrombin with a Ki value of 0.24 nM.
  11. digest GST-tagged proteins

    Thrombin is a trypsin-like allosteric serine protease. Thrombin enables site-specific cleavage of fusion proteins with an accessible Thrombin recognition sequence and can be used to digest GST-tagged proteins.
  12. Thrombin inhibitor

    Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin.
  13. synthetic thrombin inhibitor

    OM-189 is a selective synthetic thrombin inhibitor.
  14. NQO2 inhibitor

    Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor.
  15. Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
  16. indirect thrombin inhibitor

    Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) .
  17. thrombin inhibitor

    Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity.

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