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DNA Methyltransferases

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Catalog No. Product Name Application Product Information
A12785 SALE


MGMT inhibitor
Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase.
A10005 SALE

(-)-Epigallocatechin gallate

Antioxidant, antiangiogenic, antitumor agent
(-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea.
A13706 SALE


MGMT inhibitor
O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT.


DNA methyltransferase inhibitor
RG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM.

Procainamide HCl

Sodium channel blocker/DNMT inhibitor
Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor.
A14120 SALE

SGI 1027

DNMT inhibitor
SGI 1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 uM for DNMT1, DNMT3A, and DNMT3B, respectively.

SGI-110 (Guadecitabine)

DNMT inhibitor
SGI-110 is a second generation DNA-hypomethyating agent.
A10105 SALE


DNMT inhibitor
Azacitidine is a chemical analogue of the cytosine nucleoside used in DNA and RNA that is mainly used in the treatment of myelodysplastic syndrome (MDS).
A10292 SALE


DNA Methyltransferase Inhibitors
Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.

Nanaomycin A

DNMT3B inhibitor
Nanaomycin A is a selective inhibitor of DNA methyltransferase 3B (DNMT3B) with IC50 value of 500 nM.

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