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DNA Methyltransferases
Catalog No. | Product Name | Application | Product Information |
---|---|---|---|
A12785 SALE |
Lomeguatrib |
MGMT inhibitor |
Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase.
|
A10005 SALE |
(-)-Epigallocatechin gallate |
Antioxidant, antiangiogenic, antitumor agent |
(-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea.
|
A13706 SALE |
O6-Benzylguanine |
MGMT inhibitor |
O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT.
|
A13054 |
RG108 |
DNA methyltransferase inhibitor |
RG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM.
|
A14240 |
Procainamide HCl |
Sodium channel blocker/DNMT inhibitor |
Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor.
|
A14120 SALE |
SGI 1027 |
DNMT inhibitor |
SGI 1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 uM for DNMT1, DNMT3A, and DNMT3B, respectively.
|
A12744 |
SGI-110 (Guadecitabine) |
DNMT inhibitor |
SGI-110 is a second generation DNA-hypomethyating agent.
|
A10105 SALE |
Azacitidine(Vidaza) |
DNMT inhibitor |
Azacitidine is a chemical analogue of the cytosine nucleoside used in DNA and RNA that is mainly used in the treatment of myelodysplastic syndrome (MDS).
|
A10292 SALE |
Decitabine |
DNA Methyltransferase Inhibitors |
Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.
|
A13477 |
Nanaomycin A |
DNMT3B inhibitor |
Nanaomycin A is a selective inhibitor of DNA methyltransferase 3B (DNMT3B) with IC50 value of 500 nM.
|