2018-2019 AdooQ Catalog Book Available Click here to download

Opioid Receptors



20 Item(s)

per page

Set Descending Direction
Catalog No. Product Name Application Product Information
A14085

Eluxadoline

opioid receptor agonist
Eluxadoline is a novel, orally-active drug approved for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D).
A15444 SALE

TRV130 HCl (Oliceridine)

µ- opioid receptor agonist
TRV 130 HCl is a novel μ-opioid receptor (MOR) G protein-biased ligand; elicits robust G protein signaling(pEC50=8.1), with potency and efficacy similar to morphine, but with far less beta-arrestin recruitment and receptor internalization.
A15149

LY2795050

k-opioid receptor antagonist
LY2795050 is a novel selective ??-opioid Receptor (KOR) antagonist (IC50=0.72 nM) and has the potential as a PET tracer to image KOR in vivo.
A15159

Methylnaltrexone Bromide

μ-opioid antagonist
Methylnaltrexone Bromide is a pheriphally-acting ??-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation.
A11072 SALE

ADL5859 HCl

Opioid Receptor agonist
ADL5859 HCl is a highly potent and selective δ opioid receptor agonist with Ki value to be 0.84 nM and ED50 value to be 20 nM.
A13479

ADL5747

δ opioid receptor agonist
ADL5747 is a selective, nonpeptidic δ opioid receptor agonist.
A14991

Alvimopan dihydrate

µ-opioid receptor agonist
Alvimopan dihydrate(LY 246736, ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.
A14992

Alvimopan monohydrate

µ-opioid receptor agonist
Alvimopan monohydrate is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.
A15972

Naloxegol Oxalate

Opioid antagonist
Naloxegol is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation.
A14337

TRV130 (Oliceridine)

μ-opioid receptor agonist
TRV130 is an opioid drug that is under evaluation in human clinical trials for the treatment of acute severe pain. TRV130 elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less ??-arrestin 2 recruitment and receptor internalization, it displays less adverse effects than morphine.
A14187

U-69593

κ1-opioid receptor agonist
U-69593 is a potent, selective κ1-opioid receptor agonist (EC50 = 80-109 nM). Active in vivo. Antinociceptive.
A11076 SALE

JTC-801

Opioid Receptor antagonist
JTC-801 is a selective antagonist for the nociceptin receptor, also known as the ORL-1 receptor.
A10561 SALE

MCOPPB 3HCl

NOP receptor agonist
MCOPPB is a compound which acts as a potent and selective agonist for the nociceptin receptor, with a pKi of 10.07.
A11210

BRL 52537 HCl

Opioid Receptors agonist
BRL 52537 hydrochloride is a highly selective and potent κ-opioid agonist (Ki = 0.24 nM). 25 times more potent than morphine.
A11292 SALE

Alvimopan (ADL 8-2698)

Opioid antagonist
Alvimopan behaves as a peripherally acting μ-opioid antagonist. Alvimopan competitively binds to mu-opioid receptor in the gastrointestinal tract.
A11322

BAN ORL 24

NOP antagonist
BAN ORL 24 is a potent and selective NOP receptor antagonist.
A11718 SALE

Trimebutine

-
Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.
A12579 SALE

Nalfurafine hydrochloride

opioid κ-selective agonist
Nalfurafine hydrochloride is a kappa-opioid receptor agonist
A13843 SALE

Nalmefene hydrochloride

dopamine receptor agonist
Nalmefene hydrochloride is an opioid receptor antagonist.
A16155

Docusate Sodium

-
Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.

20 Item(s)

per page

Set Descending Direction