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Catalog No.
Product Name
Application
Product Information
Product Citation
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Integrin agonist
Leukadherin 1 is an allosteric activator of CD11b/CD18. Increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50 = 4 μM). -
αvβ3 integrin inhibitor
Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.- Julian Tu, .et al. , Synlett, 2020, 31, A-F
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Inhibits integrin binding to RGD motifs
RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.- Kan Zhang, .et al. , Exp Neurol, 2021, Feb 26;340:113659 PMID: 33640375
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GpIIb/IIIa antagonist
GR 144053 trihydrochloride is a potent and selective platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist. -
glycoprotein IIb/IIIa antagonist
Eptifibatide is a potent glycoprotein IIb/IIIa antagonist (GPIIb/IIIa; Kd = 120 nM) that inhibits platelet aggregation. -
α9β1/α4β1 integrin inhibitor
BOP sodium salt is a novel dual alpha9beta1/alpha4beta1 integrin inhibitor. -
LFA-1 Antagonist
BMS-688521 is a small molecule antagonist of leukocyte function associated antigen-1 (LFA-1). -
LFA-1 antagonist
Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. -
integrin α5β1 antagonist
ATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. -
α4 integrin receptor inhibitor
Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities.