DNA alkylator
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Bendamustine HCl (SDX-105)
Catalog No. A10124 Bendamustine Hydrochloride is a small molecule bifunctional DNA alkylating agent, combining a nitrogen mustard functionality with a purine-analog structure. The dense DNA-damaging functionality of Bendamustine differentiates it from other compounds used as antiproliferative agents, and these functionalities are thought to promote cell death through a variety of different pathways including apoptosis and mitotic catastrophe.
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Altretamine
Catalog No. A10059 Altretamine is classified as an alkylating antineoplastic agent.This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation. Learn More -
Cyclophosphamide monohydrate
Catalog No. A11635 Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations. Learn More -
Uramustine
Catalog No. A13473 Uramustine is a chemotherapy drug which belongs to the class of alkylating agents. Learn More -
Miriplatin hydrate
Catalog No. A15162 Miriplatin hydrate is a lipophilic platinum complex containing myristates as leaving groups, and can be easily suspended in ethyl esters of iodized fatty acids obtained from poppy seed oil. Learn More -
VAL-083
Catalog No. A15269 bi-functional alkylating agentVAL-083 is a bi-functional alkylating agent; inhibit U251 and SF188 cell growth in monolayer better than TMZ and caused apoptosis. Learn More -
Melphalan
Catalog No. A15344 DNA alkylating agentMelphalan is a cytotoxic drug used to treat multiple myeloma. Phenylamine derivative of mechorethamine. Learn More -
Thiotepa
Catalog No. A10930 Thiotepa is a polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity. Learn More