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DNA alkylator

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Catalog No. Product Name Application Product Information
A10124 SALE

Bendamustine HCl (SDX-105)


Bendamustine Hydrochloride is a small molecule bifunctional DNA alkylating agent, combining a nitrogen mustard functionality with a purine-analog structure. The dense DNA-damaging functionality of Bendamustine differentiates it from other compounds used as antiproliferative agents, and these functionalities are thought to promote cell death through a variety of different pathways including apoptosis and mitotic catastrophe.



Altretamine is classified as an alkylating antineoplastic agent.This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation.
A11635 SALE

Cyclophosphamide monohydrate

Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations.


Uramustine is a chemotherapy drug which belongs to the class of alkylating agents.

Miriplatin hydrate

Miriplatin hydrate is a lipophilic platinum complex containing myristates as leaving groups, and can be easily suspended in ethyl esters of iodized fatty acids obtained from poppy seed oil.


bi-functional alkylating agent
VAL-083 is a bi-functional alkylating agent; inhibit U251 and SF188 cell growth in monolayer better than TMZ and caused apoptosis.
A15344 SALE


DNA alkylating agent
Melphalan is a cytotoxic drug used to treat multiple myeloma. Phenylamine derivative of mechorethamine.


Thiotepa is a polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity.

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