MEK

RO4927350 a potent and highly selective non-ATP-competitive MEK1/2 inhibitor.

Refametinib, also known as RDEA119, BAY 86-9766, is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity.

Balamapimod, also known as MKI-822, is a Ras/Raf/MEK inhibitor.

RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity.

G-479 is an potent MEK inhibitor. G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.

MEK inhibitor is a potent MEK inhibitor, antitumor agent.

PD184161 is an orally-active MEK inhibitor.

NSC 80538 (1-(4-Chlorophenyl)-3-(4-fluorophenyl)thiourea) is an inhibitor of MEK Kinase PB1 Domains in Multiplex HTS Assay.