NOS
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Asymmetric dimethylarginine
Catalog No. A18704 NOS inhibitorAsymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. Learn More -
L-NIO dihydrochloride
Catalog No. A13027 NOS inhibitorL-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor. Learn More -
Diphenyleneiodonium chloride
Catalog No. A13359 GPR3 agonist/NOS/ NADPH oxidases inhibitorDiphenyleneiodonium chloride has been shown to be a potent irreversible inhibitor of NOS2 (iNOS) from macrophages and NOS3 (eNOS) from endothelial cells. Learn More -
1400W Dihydrochloride
Catalog No. A13583 INOS inhibitor1400W Dihydrochloride is a slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM). Selective over nNOS and eNOS (Ki values are 2 and 50 μM respectively). Cell-permeable and active in vivo. Learn More -
Biopterin
Catalog No. A13901 NOS cofactorBiopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 uM after 48 hrs). Learn More -
Gw274150
Catalog No. A12710 iNOS InhibitorGW274150 is a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Learn More