NOS

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  1. Asymmetric dimethylarginine

    Catalog No. A18704
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    NOS inhibitor
    Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. Learn More
  2. L-NIO dihydrochloride

    Catalog No. A13027
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    NOS inhibitor
    L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor. Learn More
  3. Diphenyleneiodonium chloride

    Catalog No. A13359
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    GPR3 agonist/NOS/ NADPH oxidases inhibitor
    Diphenyleneiodonium chloride has been shown to be a potent irreversible inhibitor of NOS2 (iNOS) from macrophages and NOS3 (eNOS) from endothelial cells. Learn More
  4. 1400W Dihydrochloride

    Catalog No. A13583
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    INOS inhibitor
    1400W Dihydrochloride is a slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM). Selective over nNOS and eNOS (Ki values are 2 and 50 μM respectively). Cell-permeable and active in vivo. Learn More
  5. Biopterin

    Catalog No. A13901
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    NOS cofactor
    Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 uM after 48 hrs). Learn More
  6. Gw274150

    Catalog No. A12710
    iNOS Inhibitor
    GW274150 is a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Learn More

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