Synthases / Synthetases
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Micafungin
Catalog No. A13270 1,3-β-D-glucan synthase inhibitorMicafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase. Learn More -
Eliglustat tartrate
Catalog No. A15466 Glucocerebroside synthase inhibitorCommonly used as the tartrate salt, Eliglustat is believed to work by inhibition of glucosylceramide synthase. Learn More -
Triacsin C
Catalog No. A13999 Triacsin C, originally isolated from Streptomyces sp., is an inhibitor of long fatty acid acyl-CoA synthetase (IC50 = 6.3 uM in Raji cells). Learn More -
Bismuth Subsalicylate
Catalog No. A14938 Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2. Learn More -
Bismuth Subcitrate Potassium
Catalog No. A14937 Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection. Learn More -
AN3365
Catalog No. A16329 leucyl-tRNA synthetase inhibitorAN3365 is a potent and selective leucyl-tRNA synthetase inhibitor. Learn More -
Buthionine Sulphoximine
Catalog No. A16202 γ-glutamylcysteine synthetase inhibitorButhionine Sulphoximine is a gamma-glutamylcysteine synthetase inhibitor potentially for the treatment of solid tumors. Learn More -
Genz-123346 free base
Catalog No. A15442 GL1 synthase InhibitorGenz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM. Learn More -
MF63
Catalog No. A11488 MPGES-1 inhibitorMF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively. Learn More -
YM-53601
Catalog No. A13483 Squalene synthase inhibitorYM-53601 is a novel squalene synthase inhibitor. It suppresses lipogenic biosynthesis and lipid secretion in rodents. Learn More -
Raltitrexed (Tomudex)
Catalog No. A10776 DNA/RNA Synthesis inhibitorRaltitrexed (Tomudex) is an inhibitor of thymidylate synthase and also is one of the strongest antimetabolites in use. Learn More -
Anidulafungin
Catalog No. A13436 glucan synthase inhibitorAnidulafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1995 and commercially developed by Eli Lilly. Anidulafungin inhibits the synthesis of ??-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi and is extensively referenced in the literature with over 400 citations. Learn More -
Nolatrexed Dihydrochloride
Catalog No. A13261 Thymidylate synthase inhibitorNolatrexed Dihydrochloride is an antifolate thymidylate synthase inhibitor. Learn More -
Caspofungin
Catalog No. A13269 1,3-β-D-glucan synthase inhibitorCaspofungin is an antifungal medicine. It is used to help the body overcome serious fungus infections, including Candida and Aspergillosis infections. It is also used to treat serious fungus infections when other medicines (e.g., amphotericin B, itraconazole) have failed. Learn More -
HQL-79
Catalog No. A12992 HQL-79 is a selective inhibitor of hematopoietic prostaglandin D (PGD) synthase, that structurally is a synthetic tetrazole compound originally prepared as a possible antihistamine. Learn More -
Alendronate sodium hydrate
Catalog No. A10050 Alendronate is a nitrogen-containing bisphosphonate that is commonly used in the treatment of osteoporosis and other metabolic bone diseases. Learn More -
Pneumocandin B0
Catalog No. A11113 β-1,3-Glucan Synthase InhibitorPneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Learn More