Synthases / Synthetases

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  1. Micafungin

    Catalog No. A13270
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    1,3-β-D-glucan synthase inhibitor
    Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase. Learn More
  2. Eliglustat tartrate

    Catalog No. A15466
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    Glucocerebroside synthase inhibitor
    Commonly used as the tartrate salt, Eliglustat is believed to work by inhibition of glucosylceramide synthase. Learn More
  3. Triacsin C

    Catalog No. A13999
    Triacsin C, originally isolated from Streptomyces sp., is an inhibitor of long fatty acid acyl-CoA synthetase (IC50 = 6.3 uM in Raji cells). Learn More
  4. Bismuth Subsalicylate

    Catalog No. A14938
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    Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2. Learn More
  5. Bismuth Subcitrate Potassium

    Catalog No. A14937
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    Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection. Learn More
  6. AN3365

    Catalog No. A16329
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    leucyl-tRNA synthetase inhibitor
    AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor. Learn More
  7. Buthionine Sulphoximine

    Catalog No. A16202
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    γ-glutamylcysteine synthetase inhibitor
    Buthionine Sulphoximine is a gamma-glutamylcysteine synthetase inhibitor potentially for the treatment of solid tumors. Learn More
  8. Genz-123346 free base

    Catalog No. A15442
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    GL1 synthase Inhibitor
    Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM. Learn More
  9. MF63

    Catalog No. A11488
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    MPGES-1 inhibitor
    MF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively. Learn More
  10. YM-53601

    Catalog No. A13483
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    Squalene synthase inhibitor
    YM-53601 is a novel squalene synthase inhibitor. It suppresses lipogenic biosynthesis and lipid secretion in rodents. Learn More
  11. Raltitrexed (Tomudex)

    Catalog No. A10776
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    DNA/RNA Synthesis inhibitor
    Raltitrexed (Tomudex) is an inhibitor of thymidylate synthase and also is one of the strongest antimetabolites in use. Learn More
  12. Anidulafungin

    Catalog No. A13436
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    glucan synthase inhibitor
    Anidulafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1995 and commercially developed by Eli Lilly. Anidulafungin inhibits the synthesis of ??-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi and is extensively referenced in the literature with over 400 citations. Learn More
  13. Nolatrexed Dihydrochloride

    Catalog No. A13261
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    Thymidylate synthase inhibitor
    Nolatrexed Dihydrochloride is an antifolate thymidylate synthase inhibitor. Learn More
  14. Caspofungin

    Catalog No. A13269
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    1,3-β-D-glucan synthase inhibitor
    Caspofungin is an antifungal medicine. It is used to help the body overcome serious fungus infections, including Candida and Aspergillosis infections. It is also used to treat serious fungus infections when other medicines (e.g., amphotericin B, itraconazole) have failed. Learn More
  15. HQL-79

    Catalog No. A12992
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    HQL-79 is a selective inhibitor of hematopoietic prostaglandin D (PGD) synthase, that structurally is a synthetic tetrazole compound originally prepared as a possible antihistamine. Learn More
  16. Alendronate sodium hydrate

    Catalog No. A10050
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    Alendronate is a nitrogen-containing bisphosphonate that is commonly used in the treatment of osteoporosis and other metabolic bone diseases. Learn More
  17. Pneumocandin B0

    Catalog No. A11113
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    β-1,3-Glucan Synthase Inhibitor
    Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Learn More

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