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Antimetabolite
Catalog No. | Product Name | Application | Product Information |
---|---|---|---|
A10251 SALE |
Flupirtine maleate |
NMDA antagonist |
Non-opioid analgesic with muscle relaxant properties.
|
A15980 |
Lometrexol disodium |
- |
Lometrexol is a folate analog antimetabolite with antineoplastic activity.
|
A10183 SALE |
Carmofur |
- |
Carmofur is a pyrimidine analogue used as an antineoplastic agent. It is a derivative of fluorouracil.
|
A10396 SALE |
Fludarabine (Fludara) |
STAT inhibitor |
Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
|
A10395 SALE |
Fludarabine Phosphate (Fludara) |
- |
Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
|
A10223 SALE |
Cladribine |
- |
Cladribine is a synthetic anti-cancer agent that mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cell's ability to process DNA.
|
A10177 SALE |
Capecitabine (Xeloda) |
- |
Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil. |
A10286 SALE |
Daphnetin |
EGFR, PKA,PKC inhibitor |
Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 µM), PKA (IC50 = 9.33 µM), and PKC (IC50 = 25 µM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent.
|
A10292 SALE |
Decitabine |
DNA Methyltransferase Inhibitors |
Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.
|
A15981 |
LY2334737 |
broad spectrum antimetabolite |
LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum antimetabolite with antineoplastic activity.
|