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Flupirtine maleate
Catalog No. A10251 NMDA antagonistNon-opioid analgesic with muscle relaxant properties. Learn More -
Decitabine
Catalog No. A10292 DNA Methyltransferase InhibitorsDecitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase. Learn More -
Daphnetin
Catalog No. A10286 EGFR, PKA,PKC inhibitorDaphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 µM), PKA (IC50 = 9.33 µM), and PKC (IC50 = 25 µM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent. Learn More -
Capecitabine (Xeloda)
Catalog No. A10177 Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.
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Cladribine
Catalog No. A10223 Cladribine is a synthetic anti-cancer agent that mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cell's ability to process DNA. Learn More -
Fludarabine Phosphate (Fludara)
Catalog No. A10395 Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells. Learn More -
Fludarabine (Fludara)
Catalog No. A10396 STAT inhibitorFludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells. Learn More -
Carmofur
Catalog No. A10183 Carmofur is a pyrimidine analogue used as an antineoplastic agent. It is a derivative of fluorouracil. Learn More -
Lometrexol disodium
Catalog No. A15980 Lometrexol is a folate analog antimetabolite with antineoplastic activity. Learn More -
LY2334737
Catalog No. A15981 broad spectrum antimetaboliteLY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum antimetabolite with antineoplastic activity. Learn More
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