Antimetabolite

10 Item(s)

per page

Set Descending Direction
  1. Flupirtine maleate

    Catalog No. A10251
    Quick View
    NMDA antagonist
    Non-opioid analgesic with muscle relaxant properties. Learn More
  2. Lometrexol disodium

    Catalog No. A15980
    Quick View
    Lometrexol is a folate analog antimetabolite with antineoplastic activity. Learn More
  3. Carmofur

    Catalog No. A10183
    Quick View
    Carmofur is a pyrimidine analogue used as an antineoplastic agent. It is a derivative of fluorouracil. Learn More
  4. Fludarabine (Fludara)

    Catalog No. A10396
    Quick View
    STAT inhibitor
    Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells. Learn More
  5. Fludarabine Phosphate (Fludara)

    Catalog No. A10395
    Quick View
    Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells. Learn More
  6. Cladribine

    Catalog No. A10223
    Quick View
    Cladribine is a synthetic anti-cancer agent that mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cell's ability to process DNA. Learn More
  7. Capecitabine (Xeloda)

    Catalog No. A10177
    Quick View

    Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

    Learn More
  8. Daphnetin

    Catalog No. A10286
    Quick View
    EGFR, PKA,PKC inhibitor
    Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 µM), PKA (IC50 = 9.33 µM), and PKC (IC50 = 25 µM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent. Learn More
  9. Decitabine

    Catalog No. A10292
    Quick View
    DNA Methyltransferase Inhibitors
    Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase. Learn More
  10. LY2334737

    Catalog No. A15981
    Quick View
    broad spectrum antimetabolite
    LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum antimetabolite with antineoplastic activity. Learn More

10 Item(s)

per page

Set Descending Direction
Rewards