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Catalog No.
Product Name
Application
Product Information
Product Citation
A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 value of 20 nM and 25 nM, respectively.
Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.
1 publications
Julian Tu, .et al. , Synlett , 2020, 31, A-F
lpha-2-integrin inhibitor
E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells.
Inhibits integrin binding to RGD motifs
RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
1 publications
Kan Zhang, .et al. , Exp Neurol , 2021, Feb 26;340:113659 PMID: 33640375
TCS2314 is a integrin very late antigen-4 (VLA-4; α4β1) antagonist with IC50 value of 4.4 nM.
BTT-3033 is a α2β1 integrin inhibitor.
α9β1/α4β1 integrin inhibitor
BOP sodium salt is a novel dual alpha9beta1/alpha4beta1 integrin inhibitor.
RWJ 50271 is a selective inhibitor of LFA-1 (lymphocyte function-associated antigen-1).
LFA-1/ICAM-1 interaction inhibitor
A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction with IC50 valueof 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion, respectively.
α4 integrin receptor inhibitor
Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities.
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